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KPV

Name: KPV
SKU: 5304
Availability: InStock

$68.99

KPV is a high-purity synthetic tripeptide, derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH), designed exclusively for laboratory research. Composed of lysine-proline-valine, this peptide is utilized to investigate anti-inflammatory, immunomodulatory, and tissue repair pathways. Supplied as a lyophilized powder for reconstitution, KPV provides researchers with a precise tool to study its effects on inflammation and healing processes in experimental models.

Category: Peptides

Description
Additional information

Description

What is KPV?

KPV is a high-purity synthetic tripeptide, derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH), designed exclusively for laboratory research. This peptide is utilized to investigate anti-inflammatory, immunomodulatory, and tissue repair pathways. Supplied as a lyophilized powder for reconstitution, KPV provides researchers with a precise tool to study its effects on inflammation and healing processes in experimental models.

KPV Structure

Molecular Formula

C₁₆H₃₀N₄O₄

Synonyms

Research Applications:

KPV is extensively studied in preclinical research for its potent anti-inflammatory and tissue-protective properties in cellular and animal models. Investigations focus on its ability to suppress pro-inflammatory cytokines (e.g., TNF-α, IL-6), modulate immune responses, and promote tissue repair, which are critical for muscle recovery and overall health. Research also explores its potential to mitigate inflammation-related metabolic dysfunction, supporting studies on weight management by addressing obesity-associated inflammation. Its role in enhancing wound healing and reducing oxidative stress makes KPV a key compound for researching recovery from muscle injury and systemic inflammatory conditions.

Research Links:

Luger, T. A., & Brzoska, T. (2006). “Alpha-MSH related peptides: A new class of anti-inflammatory and immunomodulating drugs.” Annals of the Rheumatic Diseases, 65(Suppl 3), iii52-iii55. https://pubmed.ncbi.nlm.nih.gov/17038471/
- Discusses α-MSH-derived peptides like KPV in reducing inflammation, relevant to health and recovery.
Catania, A., et al. (2004). “The melanocortin system in control of inflammation.” TheScientificWorldJournal, 4, 750-760. https://pubmed.ncbi.nlm.nih.gov/15452655/
- Explores KPV’s anti-inflammatory effects, with implications for muscle recovery and metabolic health.
Getting, S. J., et al. (2006). “The melanocortin peptide HP228 reduces inflammation and promotes tissue repair in vivo.” Journal of Leukocyte Biology, 80(5), 1104-1111. https://pubmed.ncbi.nlm.nih.gov/16908519/
- Investigates α-MSH-derived peptides, including KPV, in tissue repair and inflammation control.
Lipton, J. M., & Catania, A. (1997). “Anti-inflammatory actions of the neuroimmunomodulator α-MSH.” Immunology Today, 18(3), 140-145. https://pubmed.ncbi.nlm.nih.gov/9078685/
- Reviews α-MSH peptides like KPV in inflammation suppression, supporting muscle recovery research.
Brzoska, T., et al. (2010). “α-Melanocyte-stimulating hormone and related tripeptides: Biochemistry, anti-inflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases.” Endocrine Reviews, 31(4), 477-498. https://pubmed.ncbi.nlm.nih.gov/18334511/
- Examines KPV’s role in inflammation and tissue repair, relevant to health and weight management.

Disclaimer: This product is intended solely for research purposes and must not be used in humans or animals. Purchaser assumes full responsibility for safe and compliant use.

Additional information

CAS	40077-57-4
PubChem CID	125672
Molecular Weight	383.49 g/mol
Amino Acid Sequence	Lys-Pro-Val
PubChem Link	https://pubchem.ncbi.nlm.nih.gov/compound/125672
Product Note	For laboratory use only. Not for human or veterinary use. Proper handling and storage (-20°C) are required to maintain stability. Ensure compliance with all applicable regulations when conducting research with this compound. Peptides will arrive in a lyophilized (powder) form for maximum stability.